Advancing Vaccine Research Through Sequence Analysis
Description
This project focuses on making computational tools for B cell receptor sequence analysis more accessible to researchers. These tools help reconstruct maturation lineages and identify bottlenecks in vaccine design for diseases like HIV, influenza, and coronavirus. The goal is to create a web application, API, and visualization interface to integrate and enhance existing tools like the Armadillo web server.
A team of students will collaborate with Duke’s Office of Information Technology, faculty from Statistical Science and Computer Science, and the Duke Human Vaccine Institute. Together, they will define project requirements, develop the application, and deliver user-friendly tools to support global vaccine research efforts.
2025